Fabric Clinical NICU/PICU
Finding answers faster in the cases that matter most
Combining the benefits of proven variant prioritization algorithms with the latest in cloud computing to enable the accelerated interpretation of genetic tests in time-critical situations.
Time is of the essence, particularly with newborns who may not exhibit classic symptoms of genetic disorders. Our rapid Whole Genome Sequencing pipeline has been calibrated to dramatically reduce the time needed to detect the cause of genetic illness. The Fabric Genomics’ interpretation platform enables us to quickly analyze the results and apply the insights to pediatric patient care.
STEPHEN KINGSMORE, M.D., D.Sc., President and CEO, Rady Children’s Institute for Genomic Medicine
Accelerating WES/WGS interpretation by using advanced algorithmic prioritization to bring focus to the most phenotypically relevant variants.
Ultra-rapid Turnaround Time
For critically ill infants in the NICU/PICU, a faster diagnosis can drastically improve medical outcomes. By combining blazingly fast whole genome annotation with proven variant prioritization algorithms, Fabric Clinical NICU/PICU enables accelerated interpretation of WES/WGS tests in a matter of hours instead of days.
Infants and neonates may not yet exhibit all of the hallmark symptoms of certain diseases. Make use of the information at hand using our VAAST+Phevor algorithms to systematically prioritize variants based on their severity in conjunction with association with patient phenotype, to rapidly elucidate the most likely causative variants in each case.
Increased Diagnostic Yield
Identifying the genetic cause of disease in critically ill neonates can often lead to a diagnosis that can alter treatment plans and ultimately improve medical outcomes. Our VAAST+Phevor algorithms have been shown to identify the causative variant as the #1 candidate in roughly half of returned rare disease cases (1,300 cases returned).